ICAM-2, A Protein of Antitumor Immune Response in Mekong Giant Catfish (Pangasianodon gigas)
نویسنده
چکیده
ICAM-2 (intercellular adhesion molecule 2) or CD102 (Cluster of Differentiation 102) is type I transmembrane glycoproteins, composing 2-9 immunoglobulin-like C2-type domains. ICAM-2 plays the particular role in immune response and cell surveillance. It is concerned in innate and specific immunity, cell survival signal, apoptosis, and anticancer. EST clone of ICAM-2, from P. gigas blood cell EST libraries, showed high identity to human ICAM-2 (92%) with conserve region of ICAM N-terminal domain and part of Ig superfamily. Gene and protein of ICAM-2 has been founded in mammals. This is the first report of ICAM-2 in fish. Keywords—ICAM-2, CD102, Pangasianodon gigas, antitumor.
منابع مشابه
Title Vertical Movements of a Mekong Giant Catfish (Pangasianodon gigas) in Mae Peum Reservoir, Northern Thailand, Monitored by a Multi-Sensor Micro Data Logger
Vertical Movements of a Mekong Giant Catfish (Pangasianodon gigas) in Mae Peum Reservoir, Northern Thailand, Monitored by a Multi-Sensor Micro Data Logger Author(s) Mitamura, Hiromichi; Mitsunaga, Yasushi; Arai, Nobuaki; Yamagishi, Yukiko; Khachaphichat, Metha; Viputhanumas, Thavee Citation Zoological Science (2007), 24(7): 643-647 Issue Date 2007-07 URL http://hdl.handle.net/2433/108569 Right ...
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